Drug Information
Drug General Information | |||||
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Drug ID |
D07EEN
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Former ID |
DCL000870
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Drug Name |
Lixivaptan
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Synonyms |
VPA985; Lixivaptan [USAN:INN]; VPA-985; Lixivaptan (USAN/INN); N-[3-chloro-4-(6,11-dihydropyrrolo[2,1-c][1,4]benzodiazepine-5-carbonyl)phenyl]-5-fluoro-2-methylbenzamide
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Drug Type |
Small molecular drug
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Company |
Wyeth-Ayerst; Cardiokine
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Structure |
Download2D MOL |
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Formula |
C27H21ClFN3O2
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InChI |
InChI=1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33)
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InChIKey |
PPHTXRNHTVLQED-UHFFFAOYSA-N
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CAS Number |
CAS 168079-32-1
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PubChem Compound ID | |||||
PubChem Substance ID |
7980888, 10257813, 14883146, 33497450, 47206571, 51007980, 57352187, 85210111, 103230841, 103960062, 113473195, 125299293, 128948849, 134338769, 134339327, 134340482, 135127191, 135650528, 137263757, 137267623, 141986343, 164228268, 164761614, 176225592, 179150049, 198968309, 202821333, 215780791, 223532830, 223661309, 224998594, 227838647, 251971379
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Target and Pathway | |||||
Target(s) | Vasopressin V2 receptor | Target Info | Antagonist | [536372] | |
Pathway Interaction Database | Arf6 trafficking events | ||||
PathWhiz Pathway | Vasopressin Regulation of Water Homeostasis | ||||
References | |||||
Ref 537063 | Physical state of kappa-carrageenan modulates the mode of action of kappa-carrageenase from Pseudoalteromonas carrageenovora. Biochem J. 2009 May 1;419(3):545-53. | ||||
Ref 539415 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2238). |
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