Drug Information
Drug General Information | |||||
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Drug ID |
D07EBU
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Former ID |
DNC010889
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Drug Name |
AMG-221
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Drug Type |
Small molecular drug
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Indication | Metabolic disorders [ICD9: 270-279; ICD10:E70-E89] | Discontinued in Phase 1 | [547606] | ||
Structure |
Download2D MOL |
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Formula |
C14H22N2OS
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Canonical SMILES |
CC(C)C1(C(=O)N=C(S1)NC2CC3CCC2C3)C
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InChI |
1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1
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InChIKey |
YCNCXQNUXCHRRX-ZHPDPMBESA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Corticosteroid 11-beta-dehydrogenase, isozyme 1 | Target Info | Inhibitor | [530911] | |
NetPath Pathway | IL1 Signaling Pathway | ||||
FSH Signaling Pathway | |||||
PathWhiz Pathway | Steroidogenesis | ||||
Reactome | Glucocorticoid biosynthesis | ||||
References |
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