Drug Information
Drug General Information | |||||
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Drug ID |
D07DKC
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Former ID |
DPR000014
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Drug Name |
Apafant
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Synonyms |
Apafanto; Apafantum; Triazolodiazepine; WEB 2086BS; WEB2086; Web 2086; Apafant [USAN:INN]; Apafanto [INN-Spanish]; Apafantum [INN-Latin]; DE-081; WEB-2086; 3-(4-(2-chlorophenyl)-9-methyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-2-yl)-1-(4-morpholinyl)-1-propanone; 4-(3-(4-(o-Chlorophenyl)-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepin-2-yl)propionyl)morpholine; 4-[3-[4-(2-chlorophenyl)-9-methyl-6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]morpholine
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Drug Type |
Small molecular drug
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Company |
Santen Pharmaceutical
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Structure |
Download2D MOL |
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Formula |
C22H22ClN5O2S
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InChI |
InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
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InChIKey |
JGPJQFOROWSRRS-UHFFFAOYSA-N
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CAS Number |
CAS 105219-56-5
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PubChem Compound ID | |||||
PubChem Substance ID |
7848715, 7980891, 8190013, 12013921, 14808862, 26753288, 43122628, 47670896, 47744969, 48268088, 49993653, 50545460, 53787682, 57315807, 58108390, 85209803, 85789087, 91610602, 103186311, 103915258, 104334937, 117465116, 124891592, 124891593, 124894328, 126683013, 128272031, 134339496, 135024015, 135649947, 135651137, 135698199, 144206979, 144207143, 162023346, 163124927, 164835912, 170466052, 179149528, 184536613, 198957763, 204356799, 223468665, 223653758, 226471804, 241375892, 252156455, 252214738, 252339034
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Target and Pathway | |||||
Target(s) | Platelet-activating factor receptor | Target Info | Antagonist | [536119] | |
NetPath Pathway | IL5 Signaling Pathway | ||||
Leptin Signaling Pathway | |||||
References | |||||
Ref 536119 | Emerging drugs for ocular allergy. Expert Opin Emerg Drugs. 2005 Aug;10(3):505-20. | ||||
Ref 539170 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1860). |
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