Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07CQJ
|
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| Former ID |
DIB000212
|
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| Drug Name |
F-50040
|
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| Synonyms |
Metastatic melanoma vaccine, Pierre Fabre; P40-ELA; Metastatic melanoma vaccine, BioMerieux-Pierre Fabre; Vaccine (melanoma), Pierre Fabre; Vaccine (melanoma), BioMerieux-Pierre Fabre
|
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| Indication | Melanoma [ICD9: 172; ICD10:C43] | Discontinued in Phase 1 | [1] | ||
| Company |
Pierre Fabre SA
|
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| Target and Pathway | |||||
| Target(s) | MART-1 melanoma antigen | Target Info | Modulator | [2] | |
| Toll-like receptor 2 | Target Info | Modulator | [2] | ||
| KEGG Pathway | Phagosome | ||||
| PI3K-Akt signaling pathway | |||||
| Toll-like receptor signaling pathway | |||||
| Legionellosis | |||||
| Leishmaniasis | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Malaria | |||||
| Toxoplasmosis | |||||
| Amoebiasis | |||||
| Tuberculosis | |||||
| Hepatitis B | |||||
| Measles | |||||
| Herpes simplex infection | |||||
| Proteoglycans in cancer | |||||
| Inflammatory bowel disease (IBD) | |||||
| Rheumatoid arthritis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| TCR Signaling Pathway | |||||
| PANTHER Pathway | Toll receptor signaling pathway | ||||
| Pathway Interaction Database | Endogenous TLR signaling | ||||
| Reactome | Beta defensins | ||||
| MyD88:Mal cascade initiated on plasma membrane | |||||
| Toll Like Receptor TLR6:TLR2 Cascade | |||||
| MyD88 deficiency (TLR2/4) | |||||
| IRAK4 deficiency (TLR2/4) | |||||
| WikiPathways | Toll-like receptor signaling pathway | ||||
| IL1 and megakaryotyces in obesity | |||||
| Human Complement System | |||||
| Toll-Like Receptors Cascades | |||||
| MyD88:Mal cascade initiated on plasma membrane | |||||
| Defensins | |||||
| Regulation of toll-like receptor signaling pathway | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016041) | ||||
| REF 2 | Stability and CTL-activity of P40/ELA melanoma vaccine candidate. Biologicals. 2001 Sep-Dec;29(3-4):293-8. | ||||
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