Drug Information

Drug General Information
Drug ID
D07CPU
Former ID
DAP000929
Drug Name
Rosoxacin
Synonyms
Acrosoxacin; Eracine; Eradacil; Eradacin; Rosoxacine; Rosoxacino; Rosoxacinum; Roxadyl; Winuron; PD 107522; WIN 35213;Eradacil (TN); Rosoxacin [USAN:INN]; Rosoxacine [INN-French]; Rosoxacino [INN-Spanish]; Rosoxacinum [INN-Latin]; Roxadyl (TN); Win 35,213; Win-35123; Rosoxacin (USAN/INN); 1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid; 1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid; 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid; 1-ethyl-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [550779]
Therapeutic Class
Antiinfective Agents
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL
Formula
C17H14N2O3
Canonical SMILES
CCN1C=C(C(=O)C2=C1C=C(C=C2)C3=CC=NC=C3)C(=O)O
InChI
1S/C17H14N2O3/c1-2-19-10-14(17(21)22)16(20)13-4-3-12(9-15(13)19)11-5-7-18-8-6-11/h3-10H,2H2,1H3,(H,21,22)
InChIKey
XBPZXDSZHPDXQU-UHFFFAOYSA-N
CAS Number
CAS 40034-42-2
PubChem Compound ID
287180
PubChem Substance ID
429531, 597744, 5521217, 7849364, 8870403, 12015534, 14775839, 34827841, 46508469, 47960311, 50064766, 57401143, 76253867, 103099871, 103219336, 104474965, 117587225, 124766297, 125824915, 129665591, 134338205, 135001207, 137006106, 160964159, 162528817, 179150439, 198943144, 224863694, 226503417
SuperDrug ATC ID
J01MB01
SuperDrug CAS ID
cas=040034422
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [537724]
References
Ref 550779Drug information of Rosoxacin, 2008. eduDrugs.
Ref 537724Inhibition of Micrococcus luteus DNA gyrase by norfloxacin and 10 other quinolone carboxylic acids. Antimicrob Agents Chemother. 1986 Apr;29(4):598-601.

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