Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06YOD
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| Former ID |
DIB015948
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| Drug Name |
ZD-7717
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| Synonyms |
ICI D7717
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| Indication | Asthma [ICD10:J45] | Terminated | [1] | ||
| Company |
Zeneca Group plc
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
N1(c2c(OCC1=O)cc(Sc1cc(C3(CCOCC3)OC)cc(c1)F)cc2)C
|
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| CAS Number |
CAS 187112-64-7
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| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Modulator | [2] | |
| BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
| Resolvin D biosynthesis | |||||
| Leukotriene biosynthesis | |||||
| Lipoxin biosynthesis | |||||
| Aspirin triggered resolvin D biosynthesis | |||||
| Aspirin triggered resolvin E biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Toxoplasmosis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007338) | ||||
| REF 2 | CA patent application no. 445634, Acne treatment comprising lipoxygenase inhibitors. | ||||
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