Drug Information
Drug General Information | |||||
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Drug ID |
D06SBL
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Former ID |
DIB010382
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Drug Name |
MM-121
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Synonyms |
SAR-256212; EGFR antibodies (cancer), Merrimack; ErbB antibodies (cancer), Merrimack; MM-1x1 program (cancer), Merrimack; EGFR family tyrosine kinase receptor inhibitor (intravenous formulation/monoclonal antibody, cancer/NSCLC), Merrimack Pharmaceuticals/sanofi-aventis; ErbB3 tyrosine kinase receptor modulator (intravenous formulation/monoclonal antibody, cancer/NSCLC), Merrimack Pharmaceuticals/sanofi-aventis
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Indication | Breast cancer [ICD9: 174, 175; ICD10:C50] | Phase 2 | [523649] | ||
Company |
Merrimack pharmaceuticals; sanofi us
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Target and Pathway | |||||
Target(s) | Receptor protein-tyrosine kinase erbB-3 | Target Info | Modulator | ||
NetPath Pathway | TNFalpha Signaling Pathway | ||||
PANTHER Pathway | Cadherin signaling pathway | ||||
EGF receptor signaling pathway | |||||
Pathway Interaction Database | ErbB2/ErbB3 signaling events | ||||
ErbB receptor signaling network | |||||
a6b1 and a6b4 Integrin signaling | |||||
References |
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