| Drug General Information |
| Drug ID |
D06PZE
|
| Former ID |
DNC011124
|
| Drug Name |
TAMARIXETIN
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C16H12O7
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Cytochrome P450 1B1 |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Superpathway of tryptophan utilization
|
|
Superpathway of melatonin degradation
|
|
Melatonin degradation I
|
|
KEGG Pathway
|
Steroid hormone biosynthesis
|
|
Tryptophan metabolism
|
|
Metabolism of xenobiotics by cytochrome P450
|
|
Ovarian steroidogenesis
|
|
Chemical carcinogenesis
|
|
MicroRNAs in cancer
|
|
NetPath Pathway
|
TSH Signaling Pathway
|
|
IL4 Signaling Pathway
|
|
TGF_beta_Receptor Signaling Pathway
|
|
Reactome
|
Endogenous sterols
|
|
WikiPathways
|
Metapathway biotransformation
|
|
Estrogen metabolism
|
|
Benzo(a)pyrene metabolism
|
|
Tamoxifen metabolism
|
|
Tryptophan metabolism
|
|
Oxidation by Cytochrome P450
|
|
Nuclear Receptors Meta-Pathway
|
|
Estrogen Receptor Pathway
|
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Sulindac Metabolic Pathway
|
|
Arylhydrocarbon receptor (AhR) signaling pathway
|
|
miR-targeted genes in muscle cell - TarBase
|
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miR-targeted genes in lymphocytes - TarBase
|
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miR-targeted genes in epithelium - TarBase
|
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miR-targeted genes in adipocytes - TarBase
|
|
Phase 1 - Functionalization of compounds
|
| References |
| REF 1 | Bioorg Med Chem. 2010 Sep 1;18(17):6310-5. Epub 2010 Jul 13.Selective inhibition of methoxyflavonoids on human CYP1B1 activity. |
|---|
