Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06PLG
|
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| Drug Name |
SB-203347
|
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| Synonyms |
169527-42-8; SB-203347
|
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| Indication | Unspecified | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Target and Pathway | |||||
| Target(s) | Phospholipase A2 | Target Info | Modulator | ||
| BioCyc Pathway | Phospholipases | ||||
| KEGG Pathway | Glycerophospholipid metabolism | ||||
| Ether lipid metabolism | |||||
| Arachidonic acid metabolism | |||||
| Linoleic acid metabolism | |||||
| alpha-Linolenic acid metabolism | |||||
| Metabolic pathways | |||||
| Ras signaling pathway | |||||
| Vascular smooth muscle contraction | |||||
| Pancreatic secretion | |||||
| Fat digestion and absorption | |||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| Reactome | Acyl chain remodelling of PC | ||||
| Acyl chain remodelling of PE | |||||
| Acyl chain remodelling of PI | |||||
| WikiPathways | Glycerophospholipid biosynthesis | ||||
| References | |||||
| REF 1 | SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock. | ||||
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