Drug Information

Drug General Information
Drug ID
D06OVY
Former ID
DAP000439
Drug Name
Cefixime
Synonyms
CFIX; Cefixima; Cefiximum; Denvar; Necopen; Tricef; CL-284635; FK-027; FR-17027; Ofex (TN); Suprax (TN); Cefixime (JP15/USP/INN); (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethyloxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(carboxymethyl)oxy]imino}acetyl]amino}-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6r,7r)-7-[-2-(2-amino-thiazol-4-yl)-2-carboxymethoxyimino-acetylamino]-8-oxo-3-vinyl-5-thia-1-aza-b; 7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [536361]
Therapeutic Class
Antibiotics
Company
Wyeth Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C16H15N5O7S2
Canonical SMILES
C=CC1=C(N2C(C(C2=O)NC(=O)C(=NOCC(=O)O)C3=CSC(=N3)N)SC1)<br />C(=O)O
InChI
1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1
InChIKey
OKBVVJOGVLARMR-QSWIMTSFSA-N
CAS Number
CAS 79350-37-1
PubChem Compound ID
5362065
PubChem Substance ID
9098, 7847324, 7978875, 11654000, 12012851, 14833440, 15404783, 39384388, 46508684, 47288991, 47362877, 47957436, 48415714, 49699091, 50070784, 50124237, 57362078, 78846797, 85148376, 85661978, 85788072, 92712349, 103567682, 104133792, 114149638, 117664404, 121363201, 124800909, 126625637, 126656766, 126667588, 134337735, 135601356, 135693789, 137100974, 137240061, 143493269, 151994359, 152100554, 152242797, 162258044, 163426477, 164196526, 174560966, 175265490, 175611868, 179116601, 184812415, 198991919, 203356010
SuperDrug ATC ID
J01DD08
SuperDrug CAS ID
cas=079350371
Target and Pathway
Target(s) DNA Target Info Binder [537473]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 537473Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae. Antimicrob Agents Chemother. 2009 Jun 15.

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