Drug Information

Drug General Information
Drug ID
D06NDP
Former ID
DIB014753
Drug Name
CIGB-128
Synonyms
HeberPAG; IFN alpha2b + IFN gamma (injectable, skin cancer), CIGB
Indication Basal cell cancer [ICD9: 140-229, 173; ICD10:C44] Phase 1 [549462]
Company
Center for Genetic Engineering and Biotechnology
Target and Pathway
Target(s) Interferon alpha 2 ligand Target Info Modulator
Interferon gamma Target Info Modulator
KEGG Pathway Cytokine-cytokine receptor interaction
Regulation of autophagy
PI3K-Akt signaling pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Tuberculosis
Hepatitis C
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Autoimmune thyroid diseasehsa03050:Proteasome
HIF-1 signaling pathway
TGF-beta signaling pathway
Osteoclast differentiation
Antigen processing and presentation
T cell receptor signaling pathway
Type I diabetes mellitus
Salmonella infection
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Toxoplasmosis
Amoebiasis
Epstein-Barr virus infection
Inflammatory bowel disease (IBD)
Systemic lupus erythematosus
Rheumatoid arthritis
Allograft rejection
Graft-versus-host disease
NetPath Pathway IL2 Signaling PathwayNetPath_13:IL1 Signaling Pathway
TCR Signaling Pathway
IL2 Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Interferon-gamma signaling pathway
Pathway Interaction Database Downstream signaling in na&#xef
IL27-mediated signaling events
IL12-mediated signaling events
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
SHP2 signaling
Regulation of Telomerase
Glucocorticoid receptor regulatory network
IL2-mediated signaling events
IFN-gamma pathway
ATF-2 transcription factor network
AP-1 transcription factor network
IL23-mediated signaling events
PDGFR-alpha signaling pathway
Calcium signaling in the CD4+ TCR pathway
IL12 signaling mediated by STAT4
Reactome Interferon alpha/beta signaling
Regulation of IFNA signaling
TRAF6 mediated IRF7 activation
Factors involved in megakaryocyte development and platelet productionR-HSA-877300:Interferon gamma signaling
Regulation of IFNG signaling
WikiPathways Toll-like receptor signaling pathway
Type II interferon signaling (IFNG)
Interferon alpha/beta signaling
Regulation of toll-like receptor signaling pathwayWP619:Type II interferon signaling (IFNG)
Senescence and Autophagy in Cancer
TGF Beta Signaling Pathway
Cytokines and Inflammatory Response
Hypertrophy Model
Inflammatory Response Pathway
Aryl Hydrocarbon Receptor Pathway
IL1 and megakaryotyces in obesity
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Spinal Cord Injury
Allograft Rejection
Interferon gamma signaling
Proteasome Degradation
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 549462Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037683)

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