Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06MUZ
|
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| Former ID |
DIB000113
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| Drug Name |
SDZ-87-469
|
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| Drug Type |
Small molecular drug
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| Indication | Coronary artery disease [ICD9: 410-414, 429.2; ICD10:I20-I25] | Terminated | [1] | ||
| Company |
Novartis AG
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C19H22ClNS
|
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| Canonical SMILES |
c12scc(c1cccc2CN(C/C=C/C#CC(C)(C)C)C)Cl
|
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| CAS Number |
CAS 87906-31-8
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Squalene monooxygenase | Target Info | Modulator | [2] | |
| KEGG Pathway | Steroid biosynthesis | ||||
| Sesquiterpenoid and triterpenoid biosynthesis | |||||
| Metabolic pathways | |||||
| Biosynthesis of secondary metabolites | |||||
| Biosynthesis of antibiotics | |||||
| PathWhiz Pathway | Steroid Biosynthesis | ||||
| Reactome | Cholesterol biosynthesis | ||||
| Activation of gene expression by SREBF (SREBP) | |||||
| References | |||||
| REF 1 | Chemotherapy of fungal diseases. 1990. Page(525-550). | ||||
| REF 2 | Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother. 1992 Aug;36(8):1779-81. | ||||
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