Drug General Information
Drug ID
D06JPQ
Former ID
DIB019791
Drug Name
DY131
Synonyms
DY-131; GSK9089
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539876]
Structure
Download
2D MOL
Formula
C18H21N3O2
InChI
InChI=1S/C18H21N3O2/c1-3-21(4-2)16-9-5-14(6-10-16)13-19-20-18(23)15-7-11-17(22)12-8-15/h5-13,22H,3-4H2,1-2H3,(H,20,23)/b19-13+
InChIKey
WLKOCYWYAWBGKY-CPNJWEJPSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Estrogen-related receptor-gamma Target Info Agonist [527531]
Estrogen-related receptor-beta Target Info Agonist [527430]
References
Ref 539876(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2834).
Ref 527430Identification of an agonist ligand for estrogen-related receptors ERRbeta/gamma. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1311-3.
Ref 527531Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma. J Med Chem. 2005 May 5;48(9):3107-9.

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