| Drug General Information |
| Drug ID |
D06IEN
|
| Former ID |
DNC002548
|
| Drug Name |
2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C8H15NO6
|
| Canonical SMILES |
CC(=O)NC1C(C(C(OC1O)CO)O)O
|
| InChI |
1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1
|
| InChIKey |
OVRNDRQMDRJTHS-FMDGEEDCSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
2963, 6611, 583966, 818885, 819861, 819864, 820171, 820174, 820290, 821569, 821596, 821877, 821878, 821893, 821945, 822181, 822504, 822828, 822873, 823234, 823356, 824097, 824099, 824100, 824132, 824134, 824144, 824184, 824720, 824885, 825296, 825359, 825658, 825665, 825824, 825850, 826088, 826090, 826142, 826143, 826144, 826372, 826827, 827326, 827328, 827466, 827470, 827587, 828323, 828397
|
| Target and Pathway |
| Target(s) |
Angiotensin-converting enzyme |
Target Info |
Inhibitor |
[1]
|
|---|
| Acetylcholinesterase |
Target Info |
Inhibitor |
[1]
|
| Glucosylceramidase |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Renin-angiotensin system
|
|
Chagas disease (American trypanosomiasis)
|
|
Hypertrophic cardiomyopathy (HCM)hsa00564:Glycerophospholipid metabolism
|
|
Cholinergic synapsehsa00511:Other glycan degradation
|
|
Sphingolipid metabolism
|
|
Metabolic pathways
|
|
Lysosome
|
|
PANTHER Pathway
|
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
|
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
|
|
Nicotinic acetylcholine receptor signaling pathway
|
|
Pathway Interaction Database
|
ATF-2 transcription factor network
|
|
PathWhiz Pathway
|
Angiotensin MetabolismPW000048:Phospholipid BiosynthesisPW000148:Sphingolipid Metabolism
|
|
Reactome
|
Metabolism of Angiotensinogen to AngiotensinsR-HSA-1660662:Glycosphingolipid metabolism
|
|
WikiPathways
|
ACE Inhibitor Pathway
|
|
Metabolism of Angiotensinogen to AngiotensinsWP727:Monoamine Transport
|
|
Biogenic Amine Synthesis
|
|
Acetylcholine Synthesis
|
|
Integrated Pancreatic Cancer PathwayWP2788:Sphingolipid metabolism
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
