Drug General Information
Drug ID
D06IAQ
Former ID
DAP000893
Drug Name
Ambenonium
Synonyms
Ambenonum; Ambenonium Base; Ambenonium kation; Mytelase (TN); (2-chlorophenyl)methyl-[2-[[2-[2-[(2-chlorophenyl)methyl-diethylazaniumyl]ethylamino]-2-oxoacetyl]amino]ethyl]-diethylazanium; 2,2'-[(1,2-dioxoethane-1,2-diyl)diimino]bis[n-(2-chlorobenzyl)-n,n-diethylethanaminium]
Drug Type
Small molecular drug
Indication Myasthenia gravis [ICD9: 358; ICD10:G70.0] Approved [538427]
Therapeutic Class
Antiarrhythmic Agents
Company
Sanofi Aventis Us Llc
Structure
Download
2D MOL

3D MOL

Formula
C28H42Cl2N4O2+2
Canonical SMILES
CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)C<br />C2=CC=CC=C2Cl
InChI
1S/C28H40Cl2N4O2/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30/h9-16H,5-8,17-22H2,1-4H3/p+2
InChIKey
OMHBPUNFVFNHJK-UHFFFAOYSA-P
CAS Number
CAS 7648-98-8
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N07AA30
SuperDrug CAS ID
cas=007648988
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [536540]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 538427FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 010155.
Ref 536540Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology. 2008 Aug;33(9):2158-66. Epub 2007 Nov 21.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.