Drug Information
Drug General Information | |||||
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Drug ID |
D06HLY
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Former ID |
DAP001113
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Drug Name |
Pilocarpine
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Synonyms |
Adsorbocarpine; Almocarpine; Epicar; Isopilocarpine; Isoptocarpine; Miocarpine; Ocusert; Pilagan; Pilocarpin; Pilocarpol; Pilokarpin; Pilokarpol; Pilostat; Salagen; Spersacarpine; Syncarpine; Amistura P; Isopto carpine; Minims Pilocarpine; Ocusert pilo; Pilocarpine HCl; Pilocarpine chloride; Pilocarpine nitrate; Ocusert P 20;Beta-Pilocarpine hydrochloride; Diocarpine (TN); Isopto Carpine (TN); Mi-Pilo; Miocarpine (TN); Ocu-Carpine; Ocusert Pilo-40; Ocusert pilo-20; Pilocarpine (TN); Pilopine HS (TN); Piloptic-1; Piloptic-2; Piloptic-3; Piloptic-4; Piloptic-6; Salagen (TN); Scheinpharm (TN); Timpilo (TN); Ocusert Pilo-20 (TN); Ocusert pilo-20 (TN); P.V. Carpine Liquifilm; Pilocarpine (JAN/USP); Pilocarpine [USAN:BAN:JAN]; Piloptic-1/2; Pilocarpine Mononitrate, (3S-cis)-Isomer; Pilocarpine, Monohydrochloride, (3S-cis)-Isomer; Imidazole-5-butyric acid, alpha-ethyl-beta-(hydroxymethyl)-1-methyl-, gamma-lactone; (+)-Pilocarpine; (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one; (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one; (3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone; (3S-cis)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone; (3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone; 3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)dihydrofuran-2-one; 3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydro-2(3H)-furanone; 3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one; 3-ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydro-2(3H)-furanone; 3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
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Drug Type |
Small molecular drug
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Therapeutic Class |
Cholinergic Agents
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Company |
Alcon Laboratories
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Structure |
Download2D MOL |
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Formula |
C11H16N2O2
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InChI |
InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
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InChIKey |
QCHFTSOMWOSFHM-WPRPVWTQSA-N
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CAS Number |
CAS 54-71-7
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PubChem Compound ID | |||||
PubChem Substance ID |
9677, 605273, 7847591, 7980323, 8153662, 11113352, 11335533, 11360772, 11364001, 11366563, 11369125, 11371791, 11374095, 11377287, 11408793, 11461744, 11466477, 11467597, 11485023, 11486173, 11489100, 11490362, 11492293, 11494921, 11537578, 15195683, 15195684, 25631341, 26697419, 26751548, 29204486, 29224937, 46507475, 47213197, 47291056, 47291057, 47365110, 47440175, 47588917, 47736396, 47885334, 48110373, 48259150, 48414341, 48416432, 49698499, 49857637, 50070744, 50104139, 50104140
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ChEBI ID |
ChEBI:8207
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SuperDrug ATC ID |
N07AX01; S01EB01
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SuperDrug CAS ID |
cas=000092137
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Target and Pathway | |||||
Target(s) | Muscarinic acetylcholine receptor M5 | Target Info | Agonist | [537264], [537370] | |
References | |||||
Ref 538550 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020619. | ||||
Ref 540051 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 305). | ||||
Ref 537264 | Muscarinic activation attenuates abnormal processing of beta-amyloid precursor protein induced by cobalt chloride-mimetic hypoxia in retinal ganglion cells. Biochem Biophys Res Commun. 2009 Jun 19;384(1):110-3. Epub 2009 Apr 22. | ||||
Ref 537370 | Retinoic acid prevents virus-induced airway hyperreactivity and M2 receptor dysfunction via anti-inflammatory and antiviral effects. Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L340-6. Epub 2009 May 22. |
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