Drug General Information
Drug ID
D06FPF
Former ID
DIB015064
Drug Name
Valortim
Synonyms
Anthrax antibody, Medarex; MDX-1303; Anthrax antibody, Medarex/PharmAthene; Anti-B anthracis, Bristol Myers Squibb/PharmAthene; Anti-B anthracis PA (anthrax), Medarex/BMS/PharmAthene
Drug Type
Antibody
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Phase 1 [523304]
Company
Pharmathene
Target and Pathway
Target(s) Protective antigen Target Info [544207]
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Uptake and function of anthrax toxins
References
Ref 523304ClinicalTrials.gov (NCT01265745) Dose Escalation Study of Valortim (MDX-1303) Administered Intravenously (IV) in Healthy, Normal Subjects. U.S. National Institutes of Health.
Ref 544207Phase I Study Evaluating the Safety and Pharmacokinetics of MDX-1303, a Fully Human Monoclonal Antibody against Bacillus anthracis Protective Antigen, in Healthy Volunteers. Clin Vaccine Immunol. 2011 December; 18(12): 2136-2142.

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