Drug General Information
Drug ID	D06DSF
Former ID	DNC008334
Drug Name	5-(2-oxoindolin-5-yl)-1H-pyrrole-2-carbonitrile
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529352]
Structure		Download 2D MOL 3D MOL
Formula	C13H9N3O
Canonical SMILES	C1C2=C(C=CC(=C2)C3=CC=C(N3)C#N)NC1=O
InChI	1S/C13H9N3O/c14-7-10-2-4-11(15-10)8-1-3-12-9(5-8)6-13(17)16-12/h1-5,15H,6H2,(H,16,17)
InChIKey	TVDRXBFEEAXOTN-UHFFFAOYSA-N
PubChem Compound ID	24824217
Target and Pathway
Target(s)	Progesterone receptor	Target Info	Inhibitor	[529352]
KEGG Pathway	Oocyte meiosis
	Progesterone-mediated oocyte maturation
Pathway Interaction Database	Cellular roles of Anthrax toxin
Reactome	Nuclear signaling by ERBB4
	Nuclear Receptor transcription pathway
WikiPathways	Ovarian Infertility Genes
	Signaling by ERBB4
	Nuclear Receptors
References
Ref 529352	J Med Chem. 2008 Mar 27;51(6):1861-73. Epub 2008 Mar 5.Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).
Ref 529352	J Med Chem. 2008 Mar 27;51(6):1861-73. Epub 2008 Mar 5.Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).

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