Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06DRD
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| Former ID |
DNC006899
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| Drug Name |
Chrysamine -G
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528454] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C26H18N4O6
|
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| Canonical SMILES |
C1=CC(=CC=C1C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)[O-])N<br />N=C4C=CC(=O)C(=C4)C(=O)[O-].[Na+].[Na+]
|
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| InChI |
1S/C26H18N4O6.2Na/c31-23-11-9-19(13-21(23)25(33)34)29-27-17-5-1-15(2-6-17)16-3-7-18(8-4-16)28-30-20-10-12-24(32)22(14-20)26(35)36;;/h1-14,27-28H,(H,33,34)(H,35,36);;/q;2*+1/p-2/b29-19+,30-20+;;
|
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| InChIKey |
WRWZSSFDRPAHPA-BEYAFGAESA-L
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528454] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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