Drug Information

Drug General Information
Drug ID
D06CPL
Former ID
DNC010911
Drug Name
1-phenyl-4-(1-phenyl-1H-tetrazol-5-yl)butan-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530901]
Structure
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2D MOL

3D MOL
Formula
C17H16N4O
Canonical SMILES
C1=CC=C(C=C1)CC(=O)CCC2=NN=NN2C3=CC=CC=C3
InChI
1S/C17H16N4O/c22-16(13-14-7-3-1-4-8-14)11-12-17-18-19-20-21(17)15-9-5-2-6-10-15/h1-10H,11-13H2
InChIKey
FPYZSRILLJGVMX-UHFFFAOYSA-N
PubChem Compound ID
46890339
Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [530901]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesis
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PathWhiz Pathway Steroidogenesis
Reactome Glucocorticoid biosynthesis
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 530901Bioorg Med Chem Lett. 2010 Jun 1;20(11):3265-71. Epub 2010 Apr 18.Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles.
Ref 530901Bioorg Med Chem Lett. 2010 Jun 1;20(11):3265-71. Epub 2010 Apr 18.Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles.

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