Drug Information
Drug General Information | |||||
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Drug ID |
D06BVT
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Former ID |
DIB012312
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Drug Name |
Affitope AD-02
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Synonyms |
Alzheimer's disease vaccine 2 (AFFITOPE), AFFiRiS; Alzheimer's disease vaccine 2 (AFFITOPE), GlaxoSmithKline Biologicals
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Drug Type |
Vaccine
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Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Discontinued in Phase 2 | [548819] | ||
Company |
AFFiRiS AG
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Target and Pathway | |||||
Target(s) | Amyloid beta A4 protein | Target Info | [532655] | ||
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Degradation of the extracellular matrix | |||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
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