Drug General Information
Drug ID	D06AFP
Former ID	DNC004978
Drug Name	N-Hydroxy-2-(naphthalen-2-ylsulfanyl)-acetamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527322]
Structure		Download 2D MOL 3D MOL
Formula	C12H11NO2S
Canonical SMILES	C1=CC=C2C=C(C=CC2=C1)SCC(=O)NO
InChI	1S/C12H11NO2S/c14-12(13-15)8-16-11-6-5-9-3-1-2-4-10(9)7-11/h1-7,15H,8H2,(H,13,14)
InChIKey	GNDJOJQVOFQQBM-UHFFFAOYSA-N
PubChem Compound ID	11436221
Target and Pathway
Target(s)	Aminopeptidase N	Target Info	Inhibitor	[527322]
BioCyc Pathway	Glutathione-mediated detoxification
KEGG Pathway	Glutathione metabolism
	Metabolic pathways
	Renin-angiotensin system
	Hematopoietic cell lineage
Pathway Interaction Database	C-MYB transcription factor network
PathWhiz Pathway	Glutathione Metabolism
Reactome	Metabolism of Angiotensinogen to Angiotensins
WikiPathways	Metabolism of Angiotensinogen to Angiotensins
	Cardiac Progenitor Differentiation
	miR-targeted genes in squamous cell - TarBase
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	miR-targeted genes in leukocytes - TarBase
	Glutathione metabolism
References
Ref 527322	Bioorg Med Chem Lett. 2005 Jan 3;15(1):181-3.N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity.
Ref 527322	Bioorg Med Chem Lett. 2005 Jan 3;15(1):181-3.N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity.

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