Drug General Information
Drug ID
D06AFD
Former ID
DNC011649
Drug Name
N-Hydroxy-3-naphthalen-2-yl-N-p-tolyl-acrylamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532087]
Structure
Download
2D MOL

3D MOL

Formula
C20H17NO2
Canonical SMILES
CC1=CC=C(C=C1)N(C(=O)C=CC2=CC3=CC=CC=C3C=C2)O
InChI
1S/C20H17NO2/c1-15-6-11-19(12-7-15)21(23)20(22)13-9-16-8-10-17-4-2-3-5-18(17)14-16/h2-14,23H,1H3/b13-9+
InChIKey
MXCQZPFMNOZXSH-UKTHLTGXSA-N
PubChem Compound ID
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [532087]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.

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