| Drug General Information |
| Drug ID |
D05XNR
|
| Former ID |
DNC003919
|
| Drug Name |
2,3-Dihydro-1H-indol-5-ol
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C8H9NO
|
| Canonical SMILES |
C1CNC2=C1C=C(C=C2)O
|
| InChI |
1S/C8H9NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-2,5,9-10H,3-4H2
|
| InChIKey |
MPCXQPXCYDDJSR-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
D(2) dopamine receptor |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Rap1 signaling pathway
|
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cAMP signaling pathway
|
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Neuroactive ligand-receptor interaction
|
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Gap junction
|
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Dopaminergic synapse
|
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Parkinson's disease
|
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Cocaine addiction
|
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Alcoholism
|
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PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
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Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
|
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Dopamine receptor mediated signaling pathway
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Nicotine pharmacodynamics pathway
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Reactome
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Dopamine receptors
|
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G alpha (i) signalling events
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WikiPathways
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Hypothetical Network for Drug Addiction
|
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Monoamine GPCRs
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GPCRs, Class A Rhodopsin-like
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Genes and (Common) Pathways Underlying Drug Addiction
|
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GPCR ligand binding
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GPCR downstream signaling
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Nicotine Activity on Dopaminergic Neurons
|
| References |
| REF 1 | D4 dopamine receptor-selective compounds from the Chinese plant Phoebe chekiangensis, Bioorg. Med. Chem. Lett. 7(9):1207-1212 (1997). |
|---|
