Drug General Information |
Drug ID |
D05UFG
|
Former ID |
DCL000498
|
Drug Name |
BIBW 2992
|
Synonyms |
Afatinib; Tomtovok; Tovok; BIBW-2992; Tovok (TN); Tovok, BIBW2992; (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide; EGFR inhibitor 2nd gens
|
Drug Type |
Small molecular drug
|
Company |
Boehringer Ingelheim
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C24H25ClFN5O3
|
InChI |
InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
|
InChIKey |
ULXXDDBFHOBEHA-CWDCEQMOSA-N
|
CAS Number |
CAS 850140-72-6
|
PubChem Compound ID |
|
PubChem Substance ID |
15180141, 22579524, 40274223, 57304398, 78996079, 99432363, 103768626, 104144352, 111978343, 118049494, 123051125, 124490464, 124756933, 124896577, 125163740, 125329929, 126578844, 126666994, 126726460, 131407778, 131465104, 134222879, 134339089, 135257273, 135267496, 135727456, 136368046, 136920296, 137039955, 137263401, 142681900, 143499145, 144072463, 144115710, 151990100, 152043638, 152234944, 152258159, 152344140, 160646996, 162011458, 162037384, 162202549, 163404060, 163406016, 164041641, 164825245, 164835145, 165245589, 170502166
|
SuperDrug ATC ID |
L01XE13
|
Drug Resistance Mutation (DRM) |
Target and Pathway |
References |