TTD | Drug: D05QOF

Drug General Information
Drug ID	D05QOF
Former ID	DNC012637
Drug Name	1-Aminomethyl-3-phenyl-isochroman-5,6-diol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530404]
Structure		Download 2D MOL 3D MOL
Formula	C16H17NO3
Canonical SMILES	C1C(OC(C2=C1C(=C(C=C2)O)O)CN)C3=CC=CC=C3
InChI	1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m1/s1
InChIKey	SUHGRZPINGKYNV-HUUCEWRRSA-N
PubChem Compound ID	14809026
Target and Pathway
Target(s)	Dopamine D1 receptor	Target Info	Inhibitor	[530404]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Morphine addiction
	Alcoholism
PANTHER Pathway	Dopamine receptor mediated signaling pathway
PathWhiz Pathway	Dopamine Activation of Neurological Reward System
Reactome	Dopamine receptors
Reactome	G alpha (s) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 530404	J Med Chem. 1990 Nov;33(11):2948-50.(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist.
Ref 530404	J Med Chem. 1990 Nov;33(11):2948-50.(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist.

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Drug Information