Drug General Information
Drug ID	D05PZV
Former ID	DNC009412
Drug Name	4-(2,2'-bithiophen-5-ylmethyleneamino)phenol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529388]
Structure		Download 2D MOL 3D MOL
Formula	C15H11NOS2
Canonical SMILES	C1=CSC(=C1)C2=CC=C(S2)C=NC3=CC=C(C=C3)O
InChI	1S/C15H11NOS2/c17-12-5-3-11(4-6-12)16-10-13-7-8-15(19-13)14-2-1-9-18-14/h1-10,17H
InChIKey	UMPJRGAFFRSXRX-UHFFFAOYSA-N
PubChem Compound ID	796420
Target and Pathway
Target(s)	Collagenase 3	Target Info	Inhibitor	[529388]
NetPath Pathway	IL1 Signaling Pathway
PANTHER Pathway	Alzheimer disease-presenilin pathway
	Plasminogen activating cascade
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome	Collagen degradation
	Degradation of the extracellular matrix
	Activation of Matrix Metalloproteinases
	Assembly of collagen fibrils and other multimeric structures
WikiPathways	Endochondral Ossification
	Activation of Matrix Metalloproteinases
	Oncostatin M Signaling Pathway
	AGE/RAGE pathway
	Matrix Metalloproteinases
References
Ref 529388	Bioorg Med Chem. 2009 Feb 1;17(3):990-1005. Epub 2008 Mar 6.High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.
Ref 529388	Bioorg Med Chem. 2009 Feb 1;17(3):990-1005. Epub 2008 Mar 6.High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.