TTD | Drug: D05OVV

Drug General Information
Drug ID	D05OVV
Former ID	DNC009903
Drug Name	ST-2741
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530067]
Structure		Download 2D MOL 3D MOL
Formula	C23H25N3O2
Canonical SMILES	C1=CC=C2C(=C1)C(=CN2)C(CCCCCC(=O)NO)C3=CNC4=CC=CC=C43
InChI	1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27)
InChIKey	ZWBFOQJCRGCPED-UHFFFAOYSA-N
PubChem Compound ID	11993691
Target and Pathway
Target(s)	Histone deacetylase 6	Target Info	Inhibitor	[530067]
KEGG Pathway	Alcoholism
KEGG Pathway	Viral carcinogenesis
Pathway Interaction Database	Signaling events mediated by HDAC Class II
Pathway Interaction Database	Signaling events mediated by HDAC Class I
Reactome	NOTCH1 Intracellular Domain Regulates Transcription
	Constitutive Signaling by NOTCH1 PEST Domain Mutants
	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
	Assembly of the primary cilium
WikiPathways	Ectoderm Differentiation
	Neural Crest Differentiation
	Cell Cycle
References
Ref 530067	Bioorg Med Chem Lett. 2009 May 15;19(10):2840-3. Epub 2009 Mar 26.Exploring bis-(indolyl)methane moiety as an alternative and innovative CAP group in the design of histone deacetylase (HDAC) inhibitors.
Ref 530067	Bioorg Med Chem Lett. 2009 May 15;19(10):2840-3. Epub 2009 Mar 26.Exploring bis-(indolyl)methane moiety as an alternative and innovative CAP group in the design of histone deacetylase (HDAC) inhibitors.

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Drug Information