Drug Information

Drug General Information
Drug ID
D05ONZ
Former ID
DIB019549
Drug Name
compound 5e
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529126], [540153]
Structure
Download
2D MOL
Formula
C7H10FNO6P2
InChI
InChI=1S/C7H10FNO6P2/c8-7(16(10,11)12,17(13,14)15)4-6-2-1-3-9-5-6/h1-3,5H,4H2,(H2,10,11,12)(H2,13,14,15)
InChIKey
HHDUHWLBPDOLIL-UHFFFAOYSA-N
PubChem Compound ID
12066684
PubChem Substance ID
90084638, 103542325, 104096935, 135649662, 243177403
Target and Pathway
Target(s) Farnesyl pyrophosphatesynthetase Target Info Inhibitor [529126]
KEGG Pathway Terpenoid backbone biosynthesis
Metabolic pathways
Biosynthesis of antibiotics
Influenza A
HTLV-I infection
PathWhiz Pathway Steroid Biosynthesis
Reactome Cholesterol biosynthesis
Activation of gene expression by SREBF (SREBP)
WikiPathways Activation of Gene Expression by SREBP (SREBF)
SREBP signalling
Cholesterol Biosynthesis
References
Ref 529126Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate. J Med Chem. 2007 Nov 29;50(24):5967-75. Epub 2007 Nov 2.
Ref 540153(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3169).
Ref 529126Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate. J Med Chem. 2007 Nov 29;50(24):5967-75. Epub 2007 Nov 2.

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