Drug General Information
Drug ID	D05NAR
Former ID	DNC012908
Drug Name	Allyl 4-(aminosulfonyl)benzoate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527786]
Structure		Download 2D MOL 3D MOL
Formula	C10H11NO4S
Canonical SMILES	C=CCOC(=O)C1=CC=C(C=C1)S(=O)(=O)N
InChI	1S/C10H11NO4S/c1-2-7-15-10(12)8-3-5-9(6-4-8)16(11,13)14/h2-6H,1,7H2,(H2,11,13,14)
InChIKey	VWKMDRWBZTWKNM-UHFFFAOYSA-N
PubChem Compound ID	11536043
Target and Pathway
Target(s)	Carbonic anhydrase II	Target Info	Inhibitor	[527786]
KEGG Pathway	Nitrogen metabolism
	Proximal tubule bicarbonate reclamation
	Collecting duct acid secretion
	Gastric acid secretion
	Pancreatic secretion
	Bile secretion
NetPath Pathway	IL4 Signaling Pathway
	EGFR1 Signaling Pathway
Reactome	Erythrocytes take up carbon dioxide and release oxygen
	Erythrocytes take up oxygen and release carbon dioxide
	Reversible hydration of carbon dioxide
WikiPathways	Reversible Hydration of Carbon Dioxide
	Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
	Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 527786	Bioorg Med Chem Lett. 2005 Dec 15;15(24):5429-33. Epub 2005 Oct 6.Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II.
Ref 527786	Bioorg Med Chem Lett. 2005 Dec 15;15(24):5429-33. Epub 2005 Oct 6.Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II.

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