Drug General Information
Drug ID	D05LRD
Former ID	DNCL001932
Drug Name	BMS-933043
Indication	Psychiatric disorder [ICD9: 290-319; ICD10:F01-F99]		Phase 1	[523918]
Company	Bristol-Myers Squibb
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Neuronal acetylcholine receptor protein, alpha-7 chain	Target Info	Modulator	[550057]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Cholinergic synapse
	Nicotine addiction
	Chemical carcinogenesis
PANTHER Pathway	Alzheimer disease-amyloid secretase pathway
	Nicotinic acetylcholine receptor signaling pathway
Reactome	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 523918	ClinicalTrials.gov (NCT01605994) Multiple Ascending-Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BMS-933043 in Healthy Subjects. U.S. National Institutes of Health.
Ref 550057	Clinical pipeline report, company report or official report of Phrma.org Alzheimers 2012.

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