Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05KON
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| Former ID |
DAP000093
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| Drug Name |
Felbamate
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| Synonyms |
Felbamato; Felbamatum; Felbamyl; Felbatol; Taloxa; Essex brand of felbamate; Felbamato [Spanish]; Felbamatum [Latin]; Schering brand of felbamate; F 0778; W 554; Wallace brand 1 of felbamate; Wallace brand 2 of felbamate; ADD-03055; Carbamic acid 2-phenyltrimethylene ester; Felbamate [USAN:INN]; Felbatol (TN); Schering-Plough brand of felbamate; W-554; Carbamic acid, 2-phenyltrimethylene ester; Felbamate (USAN/INN); (3-carbamoyloxy-2-phenyl-propyl) carbamate; (3-carbamoyloxy-2-phenylpropyl) carbamate; 1,3-Propanediol, 2-phenyl-, dicarbamate; 2-Phenyl-1,3-propanediol dicarbamate; 2-Phenylpropane-1,3-diyl dicarbamate
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antiepileptic Agents
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| Company |
MedPointe
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| Structure |
|
Download2D MOL |
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| Formula |
C11H14N2O4
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| InChI |
InChI=1S/C11H14N2O4/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,14)(H2,13,15)
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| InChIKey |
WKGXYQFOCVYPAC-UHFFFAOYSA-N
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| CAS Number |
CAS 25451-15-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9704, 855835, 5299270, 7847602, 7979218, 8152115, 10515801, 11111171, 11113343, 11466947, 11528708, 12013710, 15196364, 17405087, 24277968, 26751526, 29222466, 46506375, 47589157, 47589158, 47662483, 48414310, 48416000, 50100240, 50104096, 50104097, 51299026, 53777630, 56422162, 57321729, 68530567, 81041130, 85231043, 85787789, 87350372, 90340922, 92304030, 92308149, 93166621, 99437094, 103158205, 103303660, 104171154, 104303197, 118317932, 121361313, 124749781, 124772217, 124800850, 124880084
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| SuperDrug ATC ID |
N03AX10
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| SuperDrug CAS ID |
cas=025451154
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| Target and Pathway | |||||
| Target(s) | NMDA receptor | Target Info | Antagonist | [536399], [536617], [536643] | |
| References | |||||
| Ref 536756 | Use of second-generation antiepileptic drugs in the pediatric population. Paediatr Drugs. 2008;10(4):217-54. | ||||
| Ref 540874 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5473). | ||||
| Ref 536399 | Mechanisms of action of antiepileptic drugs. Int Rev Neurobiol. 2007;81:85-110. | ||||
| Ref 536617 | Interactions of MRZ 2/576 with felbamate, lamotrigine, oxcarbazepine and topiramate in the mouse maximal electroshock-induced seizure model. Pharmacology. 2008;81(3):259-65. Epub 2008 Feb 4. | ||||
| Ref 536643 | Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptor. J Med Chem. 2008 Mar 27;51(6):1534-45. Epub 2008 Feb 27. | ||||
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