Drug General Information
Drug ID	D05IVZ
Former ID	DIB010028
Drug Name	RU-33965
Drug Type	Small molecular drug
Indication	Alzheimer disease [ICD9: 331; ICD10:G30]		Terminated	[544965]
Company	Aventis Pharma AG
Structure		Download 2D MOL 3D MOL
Formula	C16H15N3O2
Canonical SMILES	c12n(cnc1C(=O)C1CC1)c1c(C(=O)N(C2)C)cccc1
CAS Number	CAS 122321-05-5
PubChem Compound ID	129696
Target and Pathway
Target(s)	GABA A receptor	Target Info	Modulator	[526780]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 544965	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001729)
Ref 526780	Discriminative stimulus properties of RU 33965, a benzodiazepine receptor weak partial inverse agonist. Pharmacol Biochem Behav. 1992 Oct;43(2):583-8.

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