Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05HXX
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| Former ID |
DAP000199
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| Drug Name |
Tranexamic Acid
|
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| Synonyms |
AMCA; AMCHA; AMH; Amikapron; Amstat; Anvitoff; Carxamin; Cyclocapron; Cyklokapron; Emorhalt; Exacyl; Frenolyse; Hexapromin; Hexatron; Mastop; Rikavarin; Spiramin; Tamcha; Tranex; Tranexamsaeure; Tranexan; Transamin; Transamlon; Trasamlon; Ugurol; Acide tranexamique; Acido tranexamico; Acidum tranexamicum; Tranexmic acid; Tranhexamic acid; Trans AMCHA; CL 65336; DV 79; DV79; KABI 2161; LT00159441; ALBB-006013; Acide tranexamique [INN-French]; Acido tranexamico [INN-Spanish]; Acidum tranexamicum [INN-Latin]; CL-65336; Cis-AMCHA; Cyklokapron (TN); DV-79; RP 18,429; Rikavarin (TN); Rikavarin-S; T-AMCHA; Tranexamic acid cis-form; Trans-Amcha; Trans-Tranexamic acid; Transamin (TN); Cis-4-(Aminomethyl)cyclohexanecarboxylic acid; Tranexamic acid (JP15/USAN/INN); Tranexamic acid [USAN:INN:BAN:JAN]; Trans-4-(Aminomethyl)cyclohexanecarboxylic acid; Trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester; Trans-p-(Aminomethyl)cyclohexanecarboxylic; Trans-p-(Aminomethyl)cyclohexanecarboxylic acid; Cis-4-Aminomethylcyclohexane-1-carboxylic acid; Trans-1-Aminomethylcyclohexane-4-carboxylic acid; Trans-4-(Aminomethyl)cyclohexane-carboxylic acid; Trans-4-Aminomethylcyclohexane-1-carboxylic acid; Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid; Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid; Trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid; 4-(Aminomethyl)-Cyclohexanecarboxylic Acid; 4-(Aminomethyl)cyclohexanecarboxylic acid; 4-(aminomethyl)cyclohexane-1-carboxylic acid
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antifibrinolytic Agents
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| Company |
Daiichi Sankyo Pharma Development
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| Structure |
|
Download2D MOL |
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| Formula |
C8H15NO2
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| InChI |
InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
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| InChIKey |
GYDJEQRTZSCIOI-LJGSYFOKSA-N
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| CAS Number |
CAS 1197-18-8
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| PubChem Compound ID | |||||
| PubChem Substance ID |
145436, 224560, 582925, 3139692, 5659223, 7848199, 7885862, 7980823, 8149799, 8153401, 10321473, 11112474, 11335830, 11361069, 11364285, 11366847, 11369409, 11372436, 11373650, 11377571, 11462041, 11466199, 11467319, 11484425, 11485718, 11488471, 11491004, 11491861, 11495205, 14747988, 15321700, 16459820, 24846186, 24888448, 25630628, 26612264, 26679310, 26703794, 26748579, 26748580, 29224568, 37101809, 41863959, 46391649, 46508089, 47291131, 47440254, 47521547, 47588995, 47662284
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| ChEBI ID |
ChEBI:48669
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| SuperDrug ATC ID |
B02AA02
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| SuperDrug CAS ID |
cas=001197188
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| Target and Pathway | |||||
| Target(s) | Plasminogen | Target Info | Inhibitor | [536462] | |
| PANTHER Pathway | Blood coagulation | ||||
| Plasminogen activating cascade | |||||
| PathWhiz Pathway | Coagulation | ||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| Human Complement System | |||||
| Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | |||||
| Activation of Matrix Metalloproteinases | |||||
| Blood Clotting Cascade | |||||
| Dissolution of Fibrin Clot | |||||
| Folate Metabolism | |||||
| Vitamin B12 Metabolism | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| Ref 538522 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019281. | ||||
| Ref 541696 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6573). | ||||
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