Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05GZD
|
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| Former ID |
DCL000625
|
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| Drug Name |
Rilapladib
|
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| Synonyms |
SB 659032; Rilapladib (USAN)
|
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| Drug Type |
Small molecular drug
|
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| Company |
GSK
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C40H38F5N3O3S
|
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| InChI |
InChI=1S/C40H38F5N3O3S/c1-51-22-21-46-19-17-32(18-20-46)47(24-27-9-11-28(12-10-27)29-13-15-31(16-14-29)40(43,44)45)37(50)25-48-35-8-3-2-6-33(35)36(49)23-38(48)52-26-30-5-4-7-34(41)39(30)42/h2-16,23,32H,17-22,24-26H2,1H3
|
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| InChIKey |
NNBGCSGCRSCFEA-UHFFFAOYSA-N
|
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| CAS Number |
CAS 194085-75-1
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Phospholipase A2 | Target Info | Modulator | ||
| Lipoprotein-associated phospholipase A2 | Target Info | Inhibitor | [1725884] | ||
| BioCyc Pathway | Phospholipases | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| WikiPathways | Glycerophospholipid biosynthesis | ||||
| References | |||||
| Ref 542396 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7376). | ||||
| Ref 547694 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018454) | ||||
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