Drug General Information
Drug ID
D05CWG
Former ID
DNC001418
Drug Name
TEI-8362
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535494]
Structure
Download
2D MOL

3D MOL

Formula
C32H44BrN9O13S
Canonical SMILES
CC(C)(C)NCC(COC1=NSN=C1N2CCOCC2)O.C1CN=C(N1)NC2=C(C3=NC<br />=CN=C3C=C2)Br.C(=CC(=O)O)C(=O)O.C(C(C(=O)O)O)(C(=O)O)O
InChI
1S/C13H24N4O3S.C11H10BrN5.C4H6O6.C4H4O4/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17;12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8;5-1(3(7)8)2(6)4(9)10;5-3(6)1-2-4(7)8/h10,14,18H,4-9H2,1-3H3;1-4H,5-6H2,(H2,15,16,17);1-2,5-6H,(H,7,8)(H,9,10);1-2H,(H,5,6)(H,7,8)/b;;;2-1-/t10-;;1-,2-;/m0.1./s1
InChIKey
JNWSFOXBKWXBDB-NSQQTJADSA-N
CAS Number
CAS 59803-98-4
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:3175
SuperDrug ATC ID
Telapre
SuperDrug CAS ID
cas=059803984
Target and Pathway
Target(s) Leukocyte elastase Target Info Inhibitor [535494]
KEGG Pathway Transcriptional misregulation in cancer
Systemic lupus erythematosus
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
C-MYB transcription factor network
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
WikiPathways Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Human Complement System
Degradation of collagen
References
Ref 535494Neutrophil elastase inhibitors as treatment for COPD. Expert Opin Investig Drugs. 2002 Jul;11(7):965-80.
Ref 535494Neutrophil elastase inhibitors as treatment for COPD. Expert Opin Investig Drugs. 2002 Jul;11(7):965-80.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.