Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05BCA
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| Former ID |
DIB007656
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| Drug Name |
MX-4509
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| Synonyms |
MITO-4509; Parkinsons therapeutics, MitoKor; Drug screening (Parkinsons), MitoKor; Estrogen analogs (Parkinsons), Mitokor
|
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| Drug Type |
Small molecular drug
|
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| Indication | Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] | Discontinued in Phase 1 | [547955] | ||
| Company |
MitoKor; Migenix
|
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| Structure |
|
Download2D MOL |
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| Formula |
C18H24O2
|
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| Canonical SMILES |
O=S(=O)(Oc1cc2c([C@@H]3[C@H]([C@H]4[C@@]([C@@H](CC4)O)(<br />CC3)C)CC2)cc1)[O-].[Na+]
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Inhibitor | [550024] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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