| Drug General Information |
| Drug ID |
D04TQF
|
| Former ID |
DNC006915
|
| Drug Name |
1-(benzyloxy)-2-[2-(3-methoxyphenyl)ethyl]benzene
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C22H22O2
|
| Canonical SMILES |
COC1=CC=CC(=C1)CCC2=CC=CC=C2OCC3=CC=CC=C3
|
| InChI |
1S/C22H22O2/c1-23-21-12-7-10-18(16-21)14-15-20-11-5-6-13-22(20)24-17-19-8-3-2-4-9-19/h2-13,16H,14-15,17H2,1H3
|
| InChIKey |
SDDBNQDQBZPCGB-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
5-hydroxytryptamine 1A receptor |
Target Info |
Inhibitor |
[1]
|
|---|
| D(2) dopamine receptor |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
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cAMP signaling pathway
|
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Neuroactive ligand-receptor interaction
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Serotonergic synapsehsa04015:Rap1 signaling pathway
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Gap junction
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Dopaminergic synapse
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Parkinson's disease
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Cocaine addiction
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Alcoholism
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PANTHER Pathway
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Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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5HT1 type receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
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Dopamine receptor mediated signaling pathway
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Nicotine pharmacodynamics pathway
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Reactome
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Serotonin receptors
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G alpha (i) signalling eventsR-HSA-390651:Dopamine receptors
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G alpha (i) signalling events
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WikiPathways
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Serotonin HTR1 Group and FOS Pathway
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SIDS Susceptibility Pathways
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Monoamine GPCRs
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GPCRs, Class A Rhodopsin-like
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GPCR ligand binding
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GPCR downstream signalingWP666:Hypothetical Network for Drug Addiction
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Genes and (Common) Pathways Underlying Drug Addiction
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GPCR downstream signaling
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Nicotine Activity on Dopaminergic Neurons
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| References |
| REF 1 | J Med Chem. 2006 Nov 2;49(22):6607-13.Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition. |
|---|
