TTD | Drug: D04TCU

Drug General Information
Drug ID	D04TCU
Former ID	DNC005863
Drug Name	CMI-977
Drug Type	Small molecular drug
Indication	Discovery agent		Discontinued in Phase 2	[546341]
Structure		Download 2D MOL 3D MOL
Formula	C16H19FN2O4
Canonical SMILES	C1CC(OC1COC2=CC=C(C=C2)F)C#CCCN(C(=O)N)O
InChI	1S/C16H19FN2O4/c17-12-4-6-13(7-5-12)22-11-15-9-8-14(23-15)3-1-2-10-19(21)16(18)20/h4-7,14-15,21H,2,8-11H2,(H2,18,20)/t14-,15+/m1/s1
InChIKey	YANONWCPCKIWEC-CABCVRRESA-N
PubChem Compound ID	9905233
Target and Pathway
Target(s)	mRNA of human 5-lipoxygenase	Target Info	Inhibitor	[527799]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 546341	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007577)
Ref 527799	J Med Chem. 2005 Oct 20;48(21):6523-43.Designed multiple ligands. An emerging drug discovery paradigm.

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Drug Information