Drug Information
Drug General Information | |||||
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Drug ID |
D04MNL
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Former ID |
DIB001137
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Drug Name |
SERM-3339
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Synonyms |
HMR-3339; SERM compound, Aventis; 3339
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Indication | Osteoporosis [ICD9: 733.0, V07.4; ICD10:M80-M81, Z79.890] | Discontinued in Phase 2 | [547193] | ||
Company |
Hoechst Marion Roussel Inc
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CAS Number |
CAS 352233-83-1
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Target and Pathway | |||||
Target(s) | Estrogen receptor | Target Info | Modulator | [550861] | |
Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
Signaling events mediated by HDAC Class II | |||||
Plasma membrane estrogen receptor signaling | |||||
LKB1 signaling events | |||||
Regulation of Telomerase | |||||
ATF-2 transcription factor network | |||||
AP-1 transcription factor network | |||||
FOXM1 transcription factor network | |||||
Validated nuclear estrogen receptor alpha network | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
FOXA1 transcription factor network | |||||
References |
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