Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04LHG
|
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| Former ID |
DIB001467
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| Drug Name |
SP-SAP
|
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| Synonyms |
NK1-saporin conjugate, Advanced Targeting Systems; Neurokinin NK1-saporin conjugate, ATS; SP-SAP, APT; SP-SAP, Advanced Pain Therapeutics; SP-SAP, Advanced Targeting Systems; Substance P-saporin conjugate, ATS; Substance P-saporin conjugate, Advanced Targeting Systems
|
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| Indication | Cancer pain [ICD9: 140-229, 338,780; ICD10:R52, G89] | Investigative | [1] | ||
| Company |
Advanced Targeting Systems Inc
|
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| Target and Pathway | |||||
| Target(s) | Substance-P receptor | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Measles | |||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| Reactome | G alpha (q) signalling events | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Spinal Cord Injury | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 360). | ||||
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