TTD | Drug: D04HXU

Drug General Information
Drug ID	D04HXU
Former ID	DIB018612
Drug Name	4,9-anhydro-tetrodotoxin
Synonyms	4,9-anhydro-TTX; 4,9-ah-TTX
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541065]
Structure		Download 2D MOL
Formula	C11H16N3O7+
InChI	InChI=1S/C11H15N3O7/c12-8-13-6-2-4-9(17,1-15)5-3(16)10(2,14-8)7(19-6)11(18,20-4)21-5/h2-7,15-18H,1H2,(H3,12,13,14)/p+1
InChIKey	STNXQECXKDMLJK-UHFFFAOYSA-O
PubChem Compound ID	73755148
PubChem Substance ID	178102356
Target and Pathway
Target(s)	SCN8A sodium channel subunit	Target Info	Blocker (channel blocker)	[528857]
Reactome	Interaction between L1 and Ankyrins
References
Ref 541065	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5730).
Ref 528857	The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel. Am J Physiol Cell Physiol. 2007 Aug;293(2):C783-9. Epub 2007 May 23.

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Drug Information