Drug Information
Drug General Information | |||||
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Drug ID |
D04GKO
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Former ID |
DAP000912
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Drug Name |
Cilazapril
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Synonyms |
Cilazaprilum; Cilazil; Dynorm; Inhibace; Inibace; Justor; Vascace; CILAZAPRIL MONOHYDRATE; Cilazapril anhydrous;Cilazapril hydrate; Cilazaprilum [Latin]; Cilazapril (INN); Cilazapril (USAN); Cilazapril (anhydrous); Cilazapril hydrate (JAN); Cilazapril, Anhydrous; Inhibace (TN); Ro 31-2848; Ro 31-2848 monohydrate; Ro 34-2848; Ro-312848; Ro-31-2848; Cilazapril [USAN:INN:BAN:JAN]; (1S,9S)-9-(((S)-1-Carboxy-3-phenylpropyl)amino)octahydro-10-oxo-6H-pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid 9-ethyl estermonohydrate; (4S,7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid; (4S,7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid hydrate
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antihypertensive Agents
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Structure |
Download2D MOL |
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Formula |
C22H31N3O5
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InChI |
InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28)/t17-,18-,19-/m0/s1
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InChIKey |
HHHKFGXWKKUNCY-FHWLQOOXSA-N
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CAS Number |
CAS 92077-78-6
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PubChem Compound ID | |||||
PubChem Substance ID |
7978944, 8184640, 12013515, 14904662, 15427275, 43114183, 46505231, 50065358, 50515574, 51091998, 57313835, 92719467, 103589818, 104309861, 124772212, 124893758, 126620776, 126650401, 126671065, 128060846, 135022747, 137263532, 142651287, 144206524, 152090587, 160964635, 162179136, 162930181, 164788136, 178103074, 179151384, 196106617, 198942039, 210279145, 210281467, 223684401, 225144330, 226413164
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SuperDrug ATC ID |
C09AA08
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SuperDrug CAS ID |
cas=092077786
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Target and Pathway | |||||
Target(s) | Angiotensin-converting enzyme | Target Info | Inhibitor | [536694] | |
PathWhiz Pathway | Angiotensin Metabolism | ||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 541597 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6459). |
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