Drug Information
Drug General Information | |||||
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Drug ID |
D04ENK
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Former ID |
DNC001415
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Drug Name |
TCV-309
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Drug Type |
Small molecular drug
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Indication | Septic shock [ICD9: 785.52; ICD10:A41.9] | Discontinued in Phase 2 | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C30H34BrN5O7
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Canonical SMILES |
CCC[N+]1=C(C=C(C=C1)C(=O)N(CCC(=O)NCCOC(=O)N2CCC3=CC=CC<br />=C3C2)C4=CC=CC=C4)Br.[N+](=O)([O-])[O-]
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InChI |
1S/C30H33BrN4O4.NO3/c1-2-16-33-17-13-24(21-27(33)31)29(37)35(26-10-4-3-5-11-26)19-14-28(36)32-15-20-39-30(38)34-18-12-23-8-6-7-9-25(23)22-34;2-1(3)4/h3-11,13,17,21H,2,12,14-16,18-20,22H2,1H3;/q;-1/p+1
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InChIKey |
XBPVPWDSUWHDIC-UHFFFAOYSA-O
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Platelet-activating factor receptor | Target Info | Modulator | ||
KEGG Pathway | Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Staphylococcus aureus infection | |||||
NetPath Pathway | IL5 Signaling Pathway | ||||
Leptin Signaling Pathway | |||||
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (q) signalling events | |||||
Interferon gamma signaling | |||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | |||||
Small Ligand GPCRs | |||||
Interferon gamma signaling | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002130) |
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