Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03YLQ
|
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| Former ID |
DIB018143
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| Drug Name |
[125I]BE-2254
|
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| Synonyms |
HEAT; 2-{p-(4-hydroxy-3-[125I]iodophenyl)ethylaminomethyl}-tetralone; 2-[[2-(4-hydroxy-3-iodanylphenyl)ethylamino]methyl]-3,4-dihydro-2H-naphthalen-1-one
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [468122] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C19H20INO2
|
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| InChI |
InChI=1S/C19H20INO2/c20-17-11-13(5-8-18(17)22)9-10-21-12-15-7-6-14-3-1-2-4-16(14)19(15)23/h1-5,8,11,15,21-22H,6-7,9-10,12H2/i20-2
|
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| InChIKey |
DUOOAUBZMQZYLO-STTHPYEQSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Alpha-2C adrenergic receptor | Target Info | Antagonist | [533751] | |
| Alpha-1B adrenergic receptor | Target Info | Antagonist | [533751] | ||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | LPA receptor mediated events | ||||
| Reactome | Adrenoceptors | ||||
| Adrenaline signalling through Alpha-2 adrenergic receptor | |||||
| Adrenaline,noradrenaline inhibits insulin secretion | |||||
| G alpha (i) signalling events | |||||
| G alpha (z) signalling events | |||||
| Surfactant metabolismR-HSA-390696:Adrenoceptors | |||||
| G alpha (q) signalling events | |||||
| G alpha (12/13) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Platelet Aggregation (Plug Formation) | |||||
| Integration of energy metabolism | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP58:Monoamine GPCRs | |||||
| Calcium Regulation in the Cardiac Cell | |||||
| Vitamin D Receptor Pathway | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR downstream signaling | |||||
| AMPK Signaling | |||||
| References | |||||
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