Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03XGO
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| Former ID |
DIB016589
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| Drug Name |
Nematode anticoagulant proteins
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| Synonyms |
NAP-5; NAP-6; NAPs, Corvas; Nematode anticoagulant proteins, Corvas; RNAP-5; NAP-A, Corvas; NAP-B, Corvas
|
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| Indication | Angina pectoris [ICD9: 413; ICD10:I20] | Terminated | [1] | ||
| Company |
Dendreon San Diego LLC
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| Target and Pathway | |||||
| Target(s) | Coagulation factor Xa | Target Info | Modulator | ||
| KEGG Pathway | Complement and coagulation cascades | ||||
| PANTHER Pathway | Blood coagulation | ||||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
| PathWhiz Pathway | Coagulation | ||||
| Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
| Intrinsic Pathway of Fibrin Clot Formation | |||||
| Common Pathway of Fibrin Clot Formation | |||||
| Gamma-carboxylation of protein precursors | |||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| Human Complement System | |||||
| PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | |||||
| Blood Clotting Cascade | |||||
| Formation of Fibrin Clot (Clotting Cascade) | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006763) | ||||
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