Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03TOK
|
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| Former ID |
DNC006515
|
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| Drug Name |
1,6-Bis(4'-hydroxyphenyl)-hexa-1,3,5-triene
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528161] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C18H16O2
|
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| Canonical SMILES |
C1=CC(=CC=C1C=CC=CC=CC2=CC=C(C=C2)O)O
|
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| InChI |
1S/C18H16O2/c19-17-11-7-15(8-12-17)5-3-1-2-4-6-16-9-13-18(20)14-10-16/h1-14,19-20H/b2-1+,5-3+,6-4+
|
||||
| InChIKey |
FXGYAFMJWIVHGO-CRQXNEITSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528161] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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