Drug Information

Drug General Information
Drug ID
D03TGJ
Former ID
DNAP001431
Drug Name
Sorivudine
Synonyms
Usevir (TN)
Drug Type
Small molecular drug
Indication Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2] Approved [1]
Structure
Download
2D MOL

3D MOL
Formula
C11H13BrN2O6
Canonical SMILES
C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)C=CBr
InChI
1S/C11H13BrN2O6/c12-2-1-5-3-14(11(19)13-9(5)18)10-8(17)7(16)6(4-15)20-10/h1-3,6-8,10,15-17H,4H2,(H,13,18,19)/b2-1+/t6-,7-,8+,10-/m1/s1
InChIKey
GCQYYIHYQMVWLT-HQNLTJAPSA-N
CAS Number
CAS 77181-69-2
PubChem Compound ID
5282192
PubChem Substance ID
626315, 7848797, 7980638, 8616933, 12012808, 14900752, 16893378, 39315678, 50036052, 57358563, 77279719, 103265675, 113856648, 135012287, 137167326, 137246337, 179117134, 198957337, 224424237, 226461391, 241137006, 252671781
SuperDrug ATC ID
J05AB15
Target and Pathway
Target(s) HIV-1 reverse transcriptase Target Info Modulator [2], [3]
References
REF 1Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
REF 2New antivirals with activity against varicella-zoster virus. Ann Neurol. 1994;35 Suppl:S69-72.
REF 3Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.

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