Drug General Information
Drug ID
D03NPH
Former ID
DAP000690
Drug Name
Quazepam
Synonyms
Cetrane; Doral; Dormalin; Oniria; Prosedar; Quazapam; Quazepamum; Quazium; Selepam; Sch 16134; Doral (TN); Dormalin (TN); Quazepamum [INN-Latin]; Sch-161; Sch-16134; Quazepam (JAN/USP); Quazepam [USAN:BAN:INN]; Quazepam (JAN/USP/INN); 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione; 7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione; 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione
Drug Type
Small molecular drug
Indication Insomnia [ICD9: 307.41, 307.42, 327.0, 780.51, 780.52; ICD10:F51.0, G47.0] Approved [538513], [542308]
Therapeutic Class
Hypnotics and Sedatives
Company
Schering-Plough
Structure
Download
2D MOL

3D MOL

Formula
C17H11ClF4N2S
InChI
InChI=1S/C17H11ClF4N2S/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2
InChIKey
IKMPWMZBZSAONZ-UHFFFAOYSA-N
CAS Number
CAS 36735-22-5
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N05CD10
SuperDrug CAS ID
cas=036735225
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Modulator [556264]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 538513FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018708.
Ref 542308(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7288).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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