Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03NLE
|
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| Former ID |
DNC009185
|
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| Drug Name |
IGERNELLIN
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C25H40O2
|
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| Canonical SMILES |
CC1=CCCC(C1CCC(=CCCC(CCCC2=COC=C2)CO)C)(C)C
|
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| InChI |
1S/C25H40O2/c1-20(13-14-24-21(2)9-7-16-25(24,3)4)8-5-10-22(18-26)11-6-12-23-15-17-27-19-23/h8-9,15,17,19,22,24,26H,5-7,10-14,16,18H2,1-4H3/b20-8+
|
||||
| InChIKey |
UJVZMYQCMKGVLL-DNTJNYDQSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 15-lipoxygenase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Resolvin D biosynthesis | ||||
| Lipoxin biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Linoleic acid metabolism | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PANTHER Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | J Nat Prod. 2003 Feb;66(2):230-5.Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. | ||||
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